Endocrine Abstracts

Background: The insulin tolerance test (ITT) is considered the gold standard test for evaluating the ACTH–cortisol axis in patients with pituitary disease. However, the test requires time and personnel resources, and has clear contraindications. Therefore, an ACTH stimulation test is often performed instead.Objective: The objective was to compare the cortisol response acquired by ACTH stimulation and during ITT in patients with pituitary disease.</p...

Objective: Early postoperative results for the Preoperative Octreotide Treatment of Acromegaly (POTA) study has been published, and like later randomized studies we demonstrated a beneficial effect of presurgical treatment with somatostatin analogues (SSA) in GH-secreting macroadenomas when evaluated 3–4 months postoperatively. However, concerns about a potential lingering effect of SSA and thereby potential false positive results have been raised. The objective of this s...